As part of the body’s healing ability, platelets and other components in human blood migrate to the point of care. Platelets are well known to release numerous growth factors that respond to tissue injury and initiate and promote the conditions for healing.
180º PRP Hair Restoration is a proprietary system that is based on blood separation according to density using a unique separation gel. The PRP platform is available with an 11 mL PRP collection tube or 22 mL high concentration collection tube. The system allows for the preparation of pure Platelet-Rich Plasma (PRP) with optimal platelet concentrations and cellular content. Virtually, all Red Blood Cells (RBC) are eliminated from PRP and the concentration of pro-inflammatory Granulocytes (GRs) is highly reduced.
Platelet-Rich Plasma is prepared by taking a small sample of the patient’s own blood, then separating platelets from Platelet-Poor Plasma (PPP), RBC and GRs via centrifugation. Next, the PRP is collected and may be applied to the treated site. The whole preparation process only takes up to 20 minutes.
What is Platelet-Rich Plasma?
Platelet-Rich Plasma (PRP) is an autologous concentrated preparation of platelets and the associated growth factors in a small volume of plasma. Platelets are a natural source of a number of growth factors in their natural and biologically-determined ratios.
Platelet Growth Factors
Upon activation, platelets release growth factors and other molecules. These growth factors are regeneration-promoting signaling molecules, such as Platelet-Derived Growth Factor (PDGF), Transforming Growth Factor group (TGF), Epidermal Growth Factor (EGF), Vascular Endothelial Growth Factor (VEGF), Fibroblast Growth Factor (FGF) and others. These molecules are shown to regulate the healing cascade, including inflammation and cell proliferation.
The 180º Difference
- Simple: Fewer steps than other PRP (platelet-rich plasma) systems
- Superior: Optimal platelet recovery 87% ± 10%
- Safe: High-tech gel designed for safe and consistent preparation
- Fast: Centrifuge with a single spin in a matter of minutes
- Convenient Procedure: Takes less than 30 minutes
- Patient Friendly: Small volume of blood required
- Best Value: High volume PRP yield, low cost per mL
- ~6 mL PRP per 11 mL tube
- ~12 mL PRP per 22 mL tube
- Customized Concentration: Yield various volumes and concentration levels to meet patient and procedure needs
- Consistent Platelet Concentration: Allowing for predictable performance
- No Foreign Components: Virtually eliminates the risk of adverse reactions
- FDA Clearance: 510(k) number: BK110035
Frequently Asked Questions
Q: What is Platelet-Rich Plasma?
A: Autologous Platelet-Rich Plasma, also known as PRP, is a high concentration of your own platelets in a small volume of plasma.
Q: How does a provider harvest PRP?
Step 1: Utilizing a specialized blood collection tube from the Eclipse PRP® kit, a practitioner draws a small amount of blood similar to what is required for a basic lab test.
Step 2: The tube is then placed into a centrifuge which spins the blood at a very high speed, causing the platelets to separate from the other components of the blood.
Step 3: Once the platelets are concentrated into the plasma they can be applied to the patient. Activation causes platelets to release essential growth factors and signaling proteins, which are responsible for the wound-healing process.
Q: What are the growth factors and effects?
- Transforming Growth Factor (TGF)
- Promotes angiogenesis, which is the physiological process involving the synthesis of new blood vessels.
- Vascular Endothelial Growth Factor (VEGF)
- An important signaling protein involved in both angiogenesis, promoting the growth of blood vessels from pre-existing vasculature.
- Fibroblast Growth Factor (FGF)
- Promotes angiogenesis, granulation, and epithelialization.
- Platelet-Derived Growth Factor (PDGF)
- Attracts macrophages and fibroblasts to the application site. Promotes collagen growth and proteoglycan synthesis and the formation of the extracellular mix, also known as fibrin mesh.
- Interleukins, Macrophages, Keratinocytes, Endothelial Cells, Lymphocytes, Fibroblasts, Osteoblasts, Basophils, Mast Cells
- Activates fibroblast differentiation. Induces collagen and proteoglycan synthesis for healthy cell production and repair of damaged tissues.
- Collagen Stimulating Growth Factor
- Stimulates granulocyte and macrophage proliferation for the growth of healthy tissue and blood cells.
- Keratinocyte Growth Factor (KGF)
- Keratinocyte migration, differentiation, and proliferations may optimize conditions.
Q: How long does the PRP process take?
A: The blood draw takes just a couple of minutes, followed immediately by a 10-minute centrifugation. The time involved in the application varies based on which procedure is being performed.
Q: How many PRP sessions are required?
A: Your medical professional can create a treatment plan based on your individual needs.
Q: Can a PRP procedure be painful?
A: Eclipse PRP® is close to a physiologic pH, which means the product is less likely to cause a stinging or burning sensation. There may be some temporary discomfort or possible redness and inflammation at the application site, but quickly resolves.
Q: Is PRP safe?
A: Since the autologous Platelet-Rich Plasma (PRP) is produced from a patient’s own blood, there is virtually no risk of an allergic reaction or rejection.